In vivo evaluation of two tissue transglutaminase PET tracers in an orthotopic tumour xenograft mode...
In vivo evaluation of two tissue transglutaminase PET tracers in an orthotopic tumour xenograft model
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Language
English
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Background
The protein cross-linking enzyme tissue transglutaminase (TG2; EC 2.3.2.13) is associated with the pathogenesis of various diseases, including cancer. Recently, the synthesis and initial evaluation of two high-potential radiolabelled irreversible TG2 inhibitors were reported by us. In the present study, these two compounds were evalua...
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Full title
In vivo evaluation of two tissue transglutaminase PET tracers in an orthotopic tumour xenograft model
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TN_cdi_doaj_primary_oai_doaj_org_article_fa8568459fe44266838e21ee8914e3f8
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fa8568459fe44266838e21ee8914e3f8
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ISSN
2191-219X
E-ISSN
2191-219X
DOI
10.1186/s13550-018-0388-2