TREM2 dependent and independent functions of microglia in Alzheimer’s disease
TREM2 dependent and independent functions of microglia in Alzheimer’s disease
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Microglia are central players in brain innate immunity and have been the subject of extensive research in Alzheimer’s disease (AD). In this review, we aim to summarize the genetic and functional discoveries that have advanced our understanding of microglia reactivity to AD pathology. Given the heightened AD risk posed by rare variants of the microg...
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Full title
TREM2 dependent and independent functions of microglia in Alzheimer’s disease
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TN_cdi_doaj_primary_oai_doaj_org_article_fac74f1115854edf846f9eec46cfd3c4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fac74f1115854edf846f9eec46cfd3c4
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ISSN
1750-1326
E-ISSN
1750-1326
DOI
10.1186/s13024-022-00588-y
