Increased amyloidogenic processing of transgenic human APP in X11-like deficient mouse brain
Increased amyloidogenic processing of transgenic human APP in X11-like deficient mouse brain
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England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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X11-family proteins, including X11, X11-like (X11L) and X11-like 2 (X11L2), bind to the cytoplasmic domain of amyloid β-protein precursor (APP) and regulate APP metabolism. Both X11 and X11L are expressed specifically in brain, while X11L2 is expressed ubiquitously. X11L is predominantly expressed in excitatory neurons, in contrast to X11, which is...
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Full title
Increased amyloidogenic processing of transgenic human APP in X11-like deficient mouse brain
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TN_cdi_doaj_primary_oai_doaj_org_article_faea6d047d2b41ce88da6b75d865e47d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_faea6d047d2b41ce88da6b75d865e47d
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ISSN
1750-1326
E-ISSN
1750-1326
DOI
10.1186/1750-1326-5-35
