Influence of AAV vector tropism on long-term expression and Fc-γ receptor binding of an antibody tar...
Influence of AAV vector tropism on long-term expression and Fc-γ receptor binding of an antibody targeting SARS-CoV-2
About this item
Full title
Author / Creator
Wagner, Jannik T. , Müller-Schmucker, Sandra M. , Wang, Wenjun , Arnold, Philipp , Uhlig, Nadja , Issmail, Leila , Eberlein, Valentina , Damm, Dominik , Roshanbinfar, Kaveh , Ensser, Armin , Oltmanns, Friederike , Peter, Antonia Sophia , Temchura, Vladimir , Schrödel, Silke , Engel, Felix B. , Thirion, Christian , Grunwald, Thomas , Wuhrer, Manfred , Grimm, Dirk and Überla, Klaus
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Long-acting passive immunization strategies are needed to protect immunosuppressed vulnerable groups from infectious diseases. To further explore this concept for COVID-19, we constructed Adeno-associated viral (AAV) vectors encoding the human variable regions of the SARS-CoV-2 neutralizing antibody, TRES6, fused to murine constant regions. An opti...
Alternative Titles
Full title
Influence of AAV vector tropism on long-term expression and Fc-γ receptor binding of an antibody targeting SARS-CoV-2
Authors, Artists and Contributors
Author / Creator
Müller-Schmucker, Sandra M.
Wang, Wenjun
Arnold, Philipp
Uhlig, Nadja
Issmail, Leila
Eberlein, Valentina
Damm, Dominik
Roshanbinfar, Kaveh
Ensser, Armin
Oltmanns, Friederike
Peter, Antonia Sophia
Temchura, Vladimir
Schrödel, Silke
Engel, Felix B.
Thirion, Christian
Grunwald, Thomas
Wuhrer, Manfred
Grimm, Dirk
Überla, Klaus
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_fb0eb88696d04de18d534ac0c445bf7a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fb0eb88696d04de18d534ac0c445bf7a
Other Identifiers
ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-024-06529-3
