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PHF6 cooperates with SWI/SNF complexes to facilitate transcriptional progression

PHF6 cooperates with SWI/SNF complexes to facilitate transcriptional progression

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fb1fbd9e73e346ad922fc3783cc2f771

PHF6 cooperates with SWI/SNF complexes to facilitate transcriptional progression

About this item

Full title

PHF6 cooperates with SWI/SNF complexes to facilitate transcriptional progression

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2024-08, Vol.15 (1), p.7303-17, Article 7303

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Genes encoding subunits of SWI/SNF (BAF) chromatin remodeling complexes are mutated in nearly 25% of cancers. To gain insight into the mechanisms by which SWI/SNF mutations drive cancer, we contributed ten rhabdoid tumor (RT) cell lines mutant for SWI/SNF subunit
SMARCB1
to a genome-scale CRISPR–Cas9 depletion screen performed across 896 cell...

Alternative Titles

Full title

PHF6 cooperates with SWI/SNF complexes to facilitate transcriptional progression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_fb1fbd9e73e346ad922fc3783cc2f771

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fb1fbd9e73e346ad922fc3783cc2f771

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-024-51566-5

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