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Sequential action of a tRNA base editor in conversion of cytidine to pseudouridine

Sequential action of a tRNA base editor in conversion of cytidine to pseudouridine

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fb3674c997cd46d2bf5e9c008d0b569d

Sequential action of a tRNA base editor in conversion of cytidine to pseudouridine

About this item

Full title

Sequential action of a tRNA base editor in conversion of cytidine to pseudouridine

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2022-10, Vol.13 (1), p.5994-15, Article 5994

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Post-transcriptional RNA editing modulates gene expression in a condition-dependent fashion. We recently discovered C-to-Ψ editing in
Vibrio cholerae
tRNA. Here, we characterize the biogenesis, regulation, and functions of this previously undescribed RNA editing process. We show that an enzyme, TrcP, mediates the editing of C-to-U followed by...

Alternative Titles

Full title

Sequential action of a tRNA base editor in conversion of cytidine to pseudouridine

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_fb3674c997cd46d2bf5e9c008d0b569d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fb3674c997cd46d2bf5e9c008d0b569d

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-022-33714-x

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