Sequential action of a tRNA base editor in conversion of cytidine to pseudouridine
Sequential action of a tRNA base editor in conversion of cytidine to pseudouridine
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Post-transcriptional RNA editing modulates gene expression in a condition-dependent fashion. We recently discovered C-to-Ψ editing in
Vibrio cholerae
tRNA. Here, we characterize the biogenesis, regulation, and functions of this previously undescribed RNA editing process. We show that an enzyme, TrcP, mediates the editing of C-to-U followed by...
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Sequential action of a tRNA base editor in conversion of cytidine to pseudouridine
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TN_cdi_doaj_primary_oai_doaj_org_article_fb3674c997cd46d2bf5e9c008d0b569d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fb3674c997cd46d2bf5e9c008d0b569d
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-33714-x