APR-246 as a radiosensitization strategy for mutant p53 cancers treated with alpha-particles-based r...
APR-246 as a radiosensitization strategy for mutant p53 cancers treated with alpha-particles-based radiotherapy
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Radiation therapy (RT) remains a common treatment for cancer patients worldwide, despite the development of targeted biological compounds and immunotherapeutic drugs. The challenge in RT lies in delivering a lethal dose to the cancerous site while sparing the surrounding healthy tissues. Low linear energy transfer (low-LET) and high linear energy t...
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Full title
APR-246 as a radiosensitization strategy for mutant p53 cancers treated with alpha-particles-based radiotherapy
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TN_cdi_doaj_primary_oai_doaj_org_article_fb3f09d9602348ffb69155ddc6a4aab6
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fb3f09d9602348ffb69155ddc6a4aab6
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-024-06830-3
