Targeting to the non-genomic activity of retinoic acid receptor-gamma by acacetin in hepatocellular...
Targeting to the non-genomic activity of retinoic acid receptor-gamma by acacetin in hepatocellular carcinoma
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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We recently demonstrated that retinoic acid receptor-γ (RARγ) is overexpressed and acts as a tumor promoter in hepatocellular carcinoma (HCC). The oncogenic activity of RARγ is mainly attributed to its physiological interaction with p85α regulatory subunit of PI3K leading to constitutive activation of AKT. Here we report RARγ as a negative regulato...
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Targeting to the non-genomic activity of retinoic acid receptor-gamma by acacetin in hepatocellular carcinoma
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TN_cdi_doaj_primary_oai_doaj_org_article_fb891e945fc34ac6a9a63bf9fdf367da
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fb891e945fc34ac6a9a63bf9fdf367da
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-00233-5
