Synthesis, Computational Analysis, and Antiproliferative Activity of Novel Benzimidazole Acrylonitri...
Synthesis, Computational Analysis, and Antiproliferative Activity of Novel Benzimidazole Acrylonitriles as Tubulin Polymerization Inhibitors: Part 2
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Switzerland: MDPI AG
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Language
English
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Switzerland: MDPI AG
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We used classical linear and microwave-assisted synthesis methods to prepare novel N-substituted, benzimidazole-derived acrylonitriles with antiproliferative activity against several cancer cells in vitro. The most potent systems showed pronounced activity against all tested hematological cancer cell lines, with favorable selectivity towards normal...
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Synthesis, Computational Analysis, and Antiproliferative Activity of Novel Benzimidazole Acrylonitriles as Tubulin Polymerization Inhibitors: Part 2
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TN_cdi_doaj_primary_oai_doaj_org_article_fb94dfa91c564309b82611e2cd6c11cb
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fb94dfa91c564309b82611e2cd6c11cb
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ISSN
1424-8247
E-ISSN
1424-8247
DOI
10.3390/ph14101052
