Cell-to-cell variability in inducible Caspase9-mediated cell death
Cell-to-cell variability in inducible Caspase9-mediated cell death
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Author / Creator
Yuan, Yuan , Ren, Huixia , Li, Yanjun , Qin, Shanshan , Yang, Xiaojing and Tang, Chao
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
iCasp9 suicide gene has been widely used as a promising killing strategy in various cell therapies. However, different cells show significant heterogeneity in response to apoptosis inducer, posing challenges in clinical applications of killing strategy. The cause of the heterogeneity remains elusive so far. Here, by simultaneously monitoring the dy...
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Full title
Cell-to-cell variability in inducible Caspase9-mediated cell death
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TN_cdi_doaj_primary_oai_doaj_org_article_fbadef94dcfb4253b4384978262b052e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fbadef94dcfb4253b4384978262b052e
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-021-04468-z