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Proposition of a novel animal model of systemic sclerosis induced by type V collagen in C57BL/6 mice...

Proposition of a novel animal model of systemic sclerosis induced by type V collagen in C57BL/6 mice...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fbb36ef1aede4c7b82e97f0ab7dec86c

Proposition of a novel animal model of systemic sclerosis induced by type V collagen in C57BL/6 mice that reproduces fibrosis, vasculopathy and autoimmunity

About this item

Full title

Proposition of a novel animal model of systemic sclerosis induced by type V collagen in C57BL/6 mice that reproduces fibrosis, vasculopathy and autoimmunity

Publisher

England: BioMed Central Ltd

Journal title

Arthritis research & therapy, 2019-12, Vol.21 (1), p.278-12, Article 278

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Type V collagen (Col V) has the potential to become an autoantigen and has been associated with the pathogenesis of systemic sclerosis (SSc). We characterized serological, functional, and histopathological features of the skin and lung in a novel SSc murine model induced by Col V immunization.
Female C57BL/6 mice (n = 19, IMU-COLV) were subcutan...

Alternative Titles

Full title

Proposition of a novel animal model of systemic sclerosis induced by type V collagen in C57BL/6 mice that reproduces fibrosis, vasculopathy and autoimmunity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_fbb36ef1aede4c7b82e97f0ab7dec86c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fbb36ef1aede4c7b82e97f0ab7dec86c

Other Identifiers

ISSN

1478-6362,1478-6354

E-ISSN

1478-6362

DOI

10.1186/s13075-019-2052-2

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