Observation of substrate diffusion and ligand binding in enzyme crystals using high-repetition-rate...
Observation of substrate diffusion and ligand binding in enzyme crystals using high-repetition-rate mix-and-inject serial crystallography
About this item
Full title
Author / Creator
Pandey, Suraj , Calvey, George , Katz, Andrea M. , Malla, Tek Narsingh , Koua, Faisal H. M. , Martin-Garcia, Jose M. , Poudyal, Ishwor , Yang, Jay-How , Vakili, Mohammad , Yefanov, Oleksandr , Zielinski, Kara A. , Bajt, Sasa , Awel, Salah , Doerner, Katarina , Frank, Matthias , Gelisio, Luca , Jernigan, Rebecca , Kirkwood, Henry , Kloos, Marco , Koliyadu, Jayanath , Mariani, Valerio , Miller, Mitchell D. , Mills, Grant , Nelson, Garrett , Olmos, Jose L. , Sadri, Alireza , Sato, Tokushi , Tolstikova, Alexandra , Xu, Weijun , Ourmazd, Abbas , Spence, John C. H. , Schwander, Peter , Barty, Anton , Chapman, Henry N. , Fromme, Petra , Mancuso, Adrian P. , Phillips, George N. , Bean, Richard , Pollack, Lois and Schmidt, Marius
Publisher
England: International Union of Crystallography
Journal title
Language
English
Formats
Publication information
Publisher
England: International Union of Crystallography
Subjects
More information
Scope and Contents
Contents
Here, we illustrate what happens inside the catalytic cleft of an enzyme when substrate or ligand binds on single-millisecond timescales. The initial phase of the enzymatic cycle is observed with near-atomic resolution using the most advanced X-ray source currently available: the European XFEL (EuXFEL). The high repetition rate of the EuXFEL combin...
Alternative Titles
Full title
Observation of substrate diffusion and ligand binding in enzyme crystals using high-repetition-rate mix-and-inject serial crystallography
Authors, Artists and Contributors
Author / Creator
Calvey, George
Katz, Andrea M.
Malla, Tek Narsingh
Koua, Faisal H. M.
Martin-Garcia, Jose M.
Poudyal, Ishwor
Yang, Jay-How
Vakili, Mohammad
Yefanov, Oleksandr
Zielinski, Kara A.
Bajt, Sasa
Awel, Salah
Doerner, Katarina
Frank, Matthias
Gelisio, Luca
Jernigan, Rebecca
Kirkwood, Henry
Kloos, Marco
Koliyadu, Jayanath
Mariani, Valerio
Miller, Mitchell D.
Mills, Grant
Nelson, Garrett
Olmos, Jose L.
Sadri, Alireza
Sato, Tokushi
Tolstikova, Alexandra
Xu, Weijun
Ourmazd, Abbas
Spence, John C. H.
Schwander, Peter
Barty, Anton
Chapman, Henry N.
Fromme, Petra
Mancuso, Adrian P.
Phillips, George N.
Bean, Richard
Pollack, Lois
Schmidt, Marius
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_fbdbd2a5c401447a974071c858ead28e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fbdbd2a5c401447a974071c858ead28e
Other Identifiers
ISSN
2052-2525
E-ISSN
2052-2525
DOI
10.1107/S2052252521008125
