Human in vivo-generated monocyte-derived dendritic cells and macrophages cross-present antigens thro...
Human in vivo-generated monocyte-derived dendritic cells and macrophages cross-present antigens through a vacuolar pathway
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Presentation of exogenous antigens on MHC-I molecules, termed cross-presentation, is essential for cytotoxic CD8
+
T cell responses. In mice, dendritic cells (DCs) that arise from monocytes (mo-DCs) during inflammation have a key function in these responses by cross-presenting antigens locally in peripheral tissues. Whether human naturally-oc...
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Full title
Human in vivo-generated monocyte-derived dendritic cells and macrophages cross-present antigens through a vacuolar pathway
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TN_cdi_doaj_primary_oai_doaj_org_article_fbdccbe896344f34ab585eae4a11785d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fbdccbe896344f34ab585eae4a11785d
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-04985-0
