Application of Organoids in Lung Cancer Precision Medicine
Application of Organoids in Lung Cancer Precision Medicine
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Tianjin: Chinese Anti-Cancer Association Chinese Antituberculosis Association
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Chinese
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Tianjin: Chinese Anti-Cancer Association Chinese Antituberculosis Association
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Contents
肺癌的全程管理需要依靠精准医学来完成。肿瘤类器官（patient-derived organoids, PDO）模型的提出，在肺癌现有的以病理和基因等多组学检测结果为基础的精准医学决策体系之外，增加了从体外功能学模型角度出发的“黑箱”决策体系，未来有望填补分子病理指导下的难治性肺癌的治疗方案的空缺。将PDO应用于临床决策，需要验证肺癌PDO与原始癌灶多维度的一致性，更需要验证与临床试验中患者对治疗反应与PDO药敏结果的一致性。本文将对PDO模型作一简介，并在现有的肺癌精准治疗背景下，对PDO的应用场景进行综述。 Precision medicine is an approach to rational treatment selection in the overall management...
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Application of Organoids in Lung Cancer Precision Medicine
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TN_cdi_doaj_primary_oai_doaj_org_article_fc0ae1a85f3b46d9a9016463763557ac
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fc0ae1a85f3b46d9a9016463763557ac
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ISSN
1009-3419
E-ISSN
1999-6187
DOI
10.3779/j.issn.1009-3419.2020.101.20
