Intron retention is a robust marker of intertumoral heterogeneity in pancreatic ductal adenocarcinom...
Intron retention is a robust marker of intertumoral heterogeneity in pancreatic ductal adenocarcinoma
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with a 5-year survival rate of <8%. Unsupervised clustering of 76 PDAC patients based on intron retention (IR) events resulted in two clusters of tumors (IR-1 and IR-2). While gene expression-based clusters are not predictive of patient outcome in this cohort, the clusters we developed...
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Intron retention is a robust marker of intertumoral heterogeneity in pancreatic ductal adenocarcinoma
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TN_cdi_doaj_primary_oai_doaj_org_article_fc3a0c8629c1439484ba57658f1cc672
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fc3a0c8629c1439484ba57658f1cc672
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ISSN
2056-7944
E-ISSN
2056-7944
DOI
10.1038/s41525-020-00159-4