RHOA signaling defects result in impaired axon guidance in iPSC-derived neurons from patients with t...
RHOA signaling defects result in impaired axon guidance in iPSC-derived neurons from patients with tuberous sclerosis complex
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Patients with Tuberous Sclerosis Complex (TSC) show aberrant wiring of neuronal connections formed during development which may contribute to symptoms of TSC, such as intellectual disabilities, autism, and epilepsy. Yet models examining the molecular basis for axonal guidance defects in developing human neurons have not been developed. Here, we gen...
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RHOA signaling defects result in impaired axon guidance in iPSC-derived neurons from patients with tuberous sclerosis complex
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TN_cdi_doaj_primary_oai_doaj_org_article_fc9b5914dcfa4ad4b2da1ea8ef8bcc7c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fc9b5914dcfa4ad4b2da1ea8ef8bcc7c
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-22770-4
