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Endocycle-related tubular cell hypertrophy and progenitor proliferation recover renal function after...

Endocycle-related tubular cell hypertrophy and progenitor proliferation recover renal function after...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fcd2644ead064a62bdd2370d3ecae9a3

Endocycle-related tubular cell hypertrophy and progenitor proliferation recover renal function after acute kidney injury

About this item

Full title

Endocycle-related tubular cell hypertrophy and progenitor proliferation recover renal function after acute kidney injury

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2018-04, Vol.9 (1), p.1344-18, Article 1344

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Acute kidney injury (AKI) is considered largely reversible based on the capacity of surviving tubular cells to dedifferentiate and replace lost cells via cell division. Here we show by tracking individual tubular cells in conditional Pax8/Confetti mice that kidney function is  recovered after AKI despite substantial tubular cell loss. Cell cycle an...

Alternative Titles

Full title

Endocycle-related tubular cell hypertrophy and progenitor proliferation recover renal function after acute kidney injury

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_fcd2644ead064a62bdd2370d3ecae9a3

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fcd2644ead064a62bdd2370d3ecae9a3

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-018-03753-4

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