Detection and characterization of lung cancer using cell-free DNA fragmentomes
Detection and characterization of lung cancer using cell-free DNA fragmentomes
About this item
Full title
Author / Creator
Mathios, Dimitrios , Johansen, Jakob Sidenius , Cristiano, Stephen , Medina, Jamie E. , Phallen, Jillian , Larsen, Klaus R. , Bruhm, Daniel C. , Niknafs, Noushin , Ferreira, Leonardo , Adleff, Vilmos , Chiao, Jia Yuee , Leal, Alessandro , Noe, Michael , White, James R. , Arun, Adith S. , Hruban, Carolyn , Annapragada, Akshaya V. , Jensen, Sarah Østrup , Ørntoft, Mai-Britt Worm , Madsen, Anders Husted , Carvalho, Beatriz , de Wit, Meike , Carey, Jacob , Dracopoli, Nicholas C. , Maddala, Tara , Fang, Kenneth C. , Hartman, Anne-Renee , Forde, Patrick M. , Anagnostou, Valsamo , Brahmer, Julie R. , Fijneman, Remond J. A. , Nielsen, Hans Jørgen , Meijer, Gerrit A. , Andersen, Claus Lindbjerg , Mellemgaard, Anders , Bojesen, Stig E. , Scharpf, Robert B. and Velculescu, Victor E.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Non-invasive approaches for cell-free DNA (cfDNA) assessment provide an opportunity for cancer detection and intervention. Here, we use a machine learning model for detecting tumor-derived cfDNA through genome-wide analyses of cfDNA fragmentation in a prospective study of 365 individuals at risk for lung cancer. We validate the cancer detection mod...
Alternative Titles
Full title
Detection and characterization of lung cancer using cell-free DNA fragmentomes
Authors, Artists and Contributors
Author / Creator
Johansen, Jakob Sidenius
Cristiano, Stephen
Medina, Jamie E.
Phallen, Jillian
Larsen, Klaus R.
Bruhm, Daniel C.
Niknafs, Noushin
Ferreira, Leonardo
Adleff, Vilmos
Chiao, Jia Yuee
Leal, Alessandro
Noe, Michael
White, James R.
Arun, Adith S.
Hruban, Carolyn
Annapragada, Akshaya V.
Jensen, Sarah Østrup
Ørntoft, Mai-Britt Worm
Madsen, Anders Husted
Carvalho, Beatriz
de Wit, Meike
Carey, Jacob
Dracopoli, Nicholas C.
Maddala, Tara
Fang, Kenneth C.
Hartman, Anne-Renee
Forde, Patrick M.
Anagnostou, Valsamo
Brahmer, Julie R.
Fijneman, Remond J. A.
Nielsen, Hans Jørgen
Meijer, Gerrit A.
Andersen, Claus Lindbjerg
Mellemgaard, Anders
Bojesen, Stig E.
Scharpf, Robert B.
Velculescu, Victor E.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_fce9b8c82ce14c3ea1c846a1133812f2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fce9b8c82ce14c3ea1c846a1133812f2
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-24994-w
