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Discovery of novel, orally bioavailable, antileishmanial compounds using phenotypic screening

Discovery of novel, orally bioavailable, antileishmanial compounds using phenotypic screening

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fd582fbd68d94e90b34293f3995c292e

Discovery of novel, orally bioavailable, antileishmanial compounds using phenotypic screening

About this item

Full title

Discovery of novel, orally bioavailable, antileishmanial compounds using phenotypic screening

Publisher

United States: Public Library of Science

Journal title

PLoS neglected tropical diseases, 2017-12, Vol.11 (12), p.e0006157

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Leishmaniasis is a parasitic infection that afflicts approximately 12 million people worldwide. There are several limitations to the approved drug therapies for leishmaniasis, including moderate to severe toxicity, growing drug resistance, and the need for extended dosing. Moreover, miltefosine is currently the only orally available drug therapy fo...

Alternative Titles

Full title

Discovery of novel, orally bioavailable, antileishmanial compounds using phenotypic screening

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_fd582fbd68d94e90b34293f3995c292e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fd582fbd68d94e90b34293f3995c292e

Other Identifiers

ISSN

1935-2735,1935-2727

E-ISSN

1935-2735

DOI

10.1371/journal.pntd.0006157

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