Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO mice
Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO mice
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Treatment with a nicotinamide N-methyltransferase inhibitor (NNMTi; 5-amino-1-methylquinolinium) combined with low-fat diet (LD) promoted dramatic whole-body adiposity and weight loss in diet-induced obese (DIO) mice, rapidly normalizing these measures to age-matched lean animals, while LD switch alone was unable to restore these measures to age-ma...
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Full title
Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO mice
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TN_cdi_doaj_primary_oai_doaj_org_article_fd5a732a491e4a779cb2ac5a045ffece
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fd5a732a491e4a779cb2ac5a045ffece
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-03670-5
