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Breast cancer stem cells generate immune-suppressive T regulatory cells by secreting TGFβ to evade i...

Breast cancer stem cells generate immune-suppressive T regulatory cells by secreting TGFβ to evade i...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fd636c507ea044bea5ac9b5617f9980d

Breast cancer stem cells generate immune-suppressive T regulatory cells by secreting TGFβ to evade immune-elimination

About this item

Full title

Breast cancer stem cells generate immune-suppressive T regulatory cells by secreting TGFβ to evade immune-elimination

Publisher

New York: Springer US

Journal title

Discover. Oncology, 2023-12, Vol.14 (1), p.220-220, Article 220

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Cancer stem cells (CSCs), being the primary contributors in tumor initiation, metastasis, and relapse, ought to have seminal roles in evasion of immune surveillance. Tumor-promoting CD4
+
CD25
+
FOXP3

T-regulatory cells (Tregs) have been described to abolish host defense mechanisms by impeding the activities of other immune cel...

Alternative Titles

Full title

Breast cancer stem cells generate immune-suppressive T regulatory cells by secreting TGFβ to evade immune-elimination

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_fd636c507ea044bea5ac9b5617f9980d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fd636c507ea044bea5ac9b5617f9980d

Other Identifiers

ISSN

2730-6011

E-ISSN

2730-6011

DOI

10.1007/s12672-023-00787-z

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