FABP3-mediated membrane lipid saturation alters fluidity and induces ER stress in skeletal muscle wi...
FABP3-mediated membrane lipid saturation alters fluidity and induces ER stress in skeletal muscle with aging
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Sarcopenia is characterized by decreased skeletal muscle mass and function with age. Aged muscles have altered lipid compositions; however, the role and regulation of lipids are unknown. Here we report that FABP3 is upregulated in aged skeletal muscles, disrupting homeostasis via lipid remodeling. Lipidomic analyses reveal that FABP3 overexpression...
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FABP3-mediated membrane lipid saturation alters fluidity and induces ER stress in skeletal muscle with aging
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TN_cdi_doaj_primary_oai_doaj_org_article_fd99792e3593409b8c42a763dceb5467
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fd99792e3593409b8c42a763dceb5467
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-19501-6
