PGC-1α Signaling Increases GABA(A) Receptor Subunit α2 Expression, GABAergic Neurotransmission and A...
PGC-1α Signaling Increases GABA(A) Receptor Subunit α2 Expression, GABAergic Neurotransmission and Anxiety-Like Behavior in Mice
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Author / Creator
Vanaveski, Taavi , Molchanova, Svetlana , Pham, Dan Duc , Schäfer, Annika , Pajanoja, Ceren , Narvik, Jane , Srinivasan, Vignesh , Urb, Mari , Koivisto, Maria , Vasar, Eero , Timmusk, Tönis , Minkeviciene, Rimante , Eriksson, Ove , Lalowski, Maciej , Taira, Tomi , Korhonen, Laura , Voikar, Vootele and Lindholm, Dan
Publisher
Switzerland: Frontiers Research Foundation
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English
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Publisher
Switzerland: Frontiers Research Foundation
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Contents
Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is a master regulator of mitochondria biogenesis and cell stress playing a role in metabolic and degenerative diseases. In the brain PGC-1α expression has been localized mainly to GABAergic interneurons but its overall role is not fully understood. We observed here that the protei...
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Full title
PGC-1α Signaling Increases GABA(A) Receptor Subunit α2 Expression, GABAergic Neurotransmission and Anxiety-Like Behavior in Mice
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TN_cdi_doaj_primary_oai_doaj_org_article_fdada070cc85456ca0a0bfd453ceb7f0
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fdada070cc85456ca0a0bfd453ceb7f0
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ISSN
1662-5099
E-ISSN
1662-5099
DOI
10.3389/fnmol.2021.588230
