Blockage of Akt activation suppresses cadmium-induced renal tubular cellular damages through aggreph...
Blockage of Akt activation suppresses cadmium-induced renal tubular cellular damages through aggrephagy in HK-2 cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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We have reported that an environmental pollutant, cadmium, promotes cell death in the human renal tubular cells (RTCs) through hyperactivation of a serine/threonine kinase Akt. However, the molecular mechanisms downstream of Akt in this process have not been elucidated. Cadmium has a potential to accumulate misfolded proteins, and proteotoxicity is...
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Blockage of Akt activation suppresses cadmium-induced renal tubular cellular damages through aggrephagy in HK-2 cells
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TN_cdi_doaj_primary_oai_doaj_org_article_fdc97d24584d40ae824040bca9de176c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fdc97d24584d40ae824040bca9de176c
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-64579-3
