TGFBR2 mutation predicts resistance to immune checkpoint inhibitors in patients with non-small cell...
TGFBR2 mutation predicts resistance to immune checkpoint inhibitors in patients with non-small cell lung cancer
About this item
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Author / Creator
Li, Teng , Wang, Han , Xu, Jiachen , Li, Chengcheng , Zhang, Yudong , Wang, Guoqiang , Liu, Yutao , Cai, Shangli , Fang, Wenfeng , Li, Junling and Wang, Zhijie
Publisher
London, England: SAGE Publications
Journal title
Language
English
Formats
Publication information
Publisher
London, England: SAGE Publications
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Scope and Contents
Contents
Background:
Resistance or even hyper-progression to immune checkpoint inhibitors (ICIs) manifesting as accelerated disease progression or death has impeded the clinical use of ICIs. The transforming growth factor beta (TGFβ) receptor pathway has been identified in contributing to immune dysfunction, which might be associated with resistance to I...
Alternative Titles
Full title
TGFBR2 mutation predicts resistance to immune checkpoint inhibitors in patients with non-small cell lung cancer
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_fdeaacf7e062492a8163640826c13b78
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fdeaacf7e062492a8163640826c13b78
Other Identifiers
ISSN
1758-8359,1758-8340
E-ISSN
1758-8359
DOI
10.1177/17588359211038477
