Insights into pancreatic β cell energy metabolism using rodent β cell models
Insights into pancreatic β cell energy metabolism using rodent β cell models
About this item
Full title
Author / Creator
Morten, Karl J , Potter, Michelle , Badder, Luned , Sivathondan, Pamela , Dragovic, Rebecca , Neumann, Abigale , Gavin, James , Shrestha, Roshan , Reilly, Svetlana , Phadwal, Kanchan , Lodge, Tiffany A , Borzychowski, Angela , Cookson, Sharon , Mitchell, Corey , Morovat, Alireza , Simon, Anna Katharina , Uusimaa, Johanna , Hynes, James and Poulton, Joanna
Publisher
England: Wellcome Trust Limited
Journal title
Language
English
Formats
Publication information
Publisher
England: Wellcome Trust Limited
Subjects
More information
Scope and Contents
Contents
Mitochondrial diabetes is primarily caused by β-cell failure, a cell type whose unique properties are important in pathogenesis.
By reducing glucose, we induced energetic stress in two rodent β-cell models to assess effects on cellular function.
Culturing rat insulin-secreting INS-1 cells in low glucose conditions caused a rapid reduction in...
Alternative Titles
Full title
Insights into pancreatic β cell energy metabolism using rodent β cell models
Authors, Artists and Contributors
Author / Creator
Potter, Michelle
Badder, Luned
Sivathondan, Pamela
Dragovic, Rebecca
Neumann, Abigale
Gavin, James
Shrestha, Roshan
Reilly, Svetlana
Phadwal, Kanchan
Lodge, Tiffany A
Borzychowski, Angela
Cookson, Sharon
Mitchell, Corey
Morovat, Alireza
Simon, Anna Katharina
Uusimaa, Johanna
Hynes, James
Poulton, Joanna
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_fe13c9ee59e34f6b87ed8a15400ee82f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fe13c9ee59e34f6b87ed8a15400ee82f
Other Identifiers
ISSN
2398-502X
E-ISSN
2398-502X
DOI
10.12688/wellcomeopenres.10535.3
