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Expression of RMRP RNA is regulated in chondrocyte hypertrophy and determines chondrogenic different...

Expression of RMRP RNA is regulated in chondrocyte hypertrophy and determines chondrogenic different...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fe524fe2574a400f80a3473252df828a

Expression of RMRP RNA is regulated in chondrocyte hypertrophy and determines chondrogenic differentiation

About this item

Full title

Expression of RMRP RNA is regulated in chondrocyte hypertrophy and determines chondrogenic differentiation

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2017-07, Vol.7 (1), p.6440-15, Article 6440

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Mutations in the
RMRP
-gene, encoding the lncRNA component of the RNase MRP complex, are the origin of cartilage-hair hypoplasia. Cartilage-hair hypoplasia is associated with severe dwarfism caused by impaired skeletal development. However, it is not clear why mutations in
RMRP
RNA lead to skeletal dysplasia. Since chondrogenic differen...

Alternative Titles

Full title

Expression of RMRP RNA is regulated in chondrocyte hypertrophy and determines chondrogenic differentiation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_fe524fe2574a400f80a3473252df828a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fe524fe2574a400f80a3473252df828a

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-017-06809-5

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