Activation of the MAC1-ERK1/2-NOX2 Pathway Is Required for LPS-Induced Sustaining Reactive Microglio...
Activation of the MAC1-ERK1/2-NOX2 Pathway Is Required for LPS-Induced Sustaining Reactive Microgliosis, Chronic Neuroinflammation and Neurodegeneration
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Author / Creator
Chen, Shih-Heng , Han, Shuangyu , Hu, Chih-Fen , Zhou, Ran , Gao, Yun , Tu, Dezhen , Gao, Huiming , Feng, Jing , Wang, Yubao , Lu, Ru-Band and Hong, Jau-Shyong
Publisher
Switzerland: MDPI AG
Journal title
Language
English
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Publication information
Publisher
Switzerland: MDPI AG
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Scope and Contents
Contents
Recent studies suggest that improper resolution of acute neuroinflammation may lead to long-lasting low-grade chronic neuroinflammation and drive progressive neurodegeneration. However, the molecular mechanism underlying the transition from acute to chronic neuroinflammation remains unclear. The main purpose of this study was to search for potentia...
Alternative Titles
Full title
Activation of the MAC1-ERK1/2-NOX2 Pathway Is Required for LPS-Induced Sustaining Reactive Microgliosis, Chronic Neuroinflammation and Neurodegeneration
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TN_cdi_doaj_primary_oai_doaj_org_article_fe60fcf208ab44a58c0fad35d2e06ab6
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fe60fcf208ab44a58c0fad35d2e06ab6
Other Identifiers
ISSN
2076-3921
E-ISSN
2076-3921
DOI
10.3390/antiox11061202
