The activation mechanism of Irga6, an interferon-inducible GTPase contributing to mouse resistance a...
The activation mechanism of Irga6, an interferon-inducible GTPase contributing to mouse resistance against Toxoplasma gondii
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
The interferon-inducible immunity-related GTPases (IRG proteins/p47 GTPases) are a distinctive family of GTPases that function as powerful cell-autonomous resistance factors. The IRG protein, Irga6 (IIGP1), participates in the disruption of the vacuolar membrane surrounding the intracellular parasite, Toxoplasma gondii, through which it communicate...
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Full title
The activation mechanism of Irga6, an interferon-inducible GTPase contributing to mouse resistance against Toxoplasma gondii
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TN_cdi_doaj_primary_oai_doaj_org_article_fe663165b900402192ec97cb203053c7
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fe663165b900402192ec97cb203053c7
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ISSN
1741-7007
E-ISSN
1741-7007
DOI
10.1186/1741-7007-9-7
