HIF-1α is a key regulator in potentiating suppressor activity and limiting the microbicidal capacity...
HIF-1α is a key regulator in potentiating suppressor activity and limiting the microbicidal capacity of MDSC-like cells during visceral leishmaniasis
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Leishmania donovani is known to induce myelopoiesis and to dramatically increase extramedullary myelopoiesis. This results in splenomegaly, which is then accompanied by disruption of the splenic microarchitecture, a chronic inflammatory environment, and immunosuppression. Chronically inflamed tissues are typically hypoxic. The role of hypoxia on my...
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HIF-1α is a key regulator in potentiating suppressor activity and limiting the microbicidal capacity of MDSC-like cells during visceral leishmaniasis
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TN_cdi_doaj_primary_oai_doaj_org_article_fe6e241d5a9848fe8447caafbe3fb7e5
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fe6e241d5a9848fe8447caafbe3fb7e5
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1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1006616
