A cookbook for DNase Hi-C
A cookbook for DNase Hi-C
About this item
Full title
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Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
The Hi-C technique is widely employed to study the 3-dimensional chromatin architecture and to assemble genomes. The conventional in situ Hi-C protocol employs restriction enzymes to digest chromatin, which results in nonuniform genomic coverage. Using sequence-agnostic restriction enzymes, such as DNAse I, could help to overcome this limitation.
Alternative Titles
Full title
A cookbook for DNase Hi-C
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_fec92906eb854cc3a364233c77852460
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fec92906eb854cc3a364233c77852460
Other Identifiers
ISSN
1756-8935
E-ISSN
1756-8935
DOI
10.1186/s13072-021-00389-5
