From a genome-wide screen of RNAi molecules against SARS-CoV-2 to a validated broad-spectrum and pot...
From a genome-wide screen of RNAi molecules against SARS-CoV-2 to a validated broad-spectrum and potent prophylaxis
About this item
Full title
Author / Creator
Yogev, Ohad , Weissbrod, Omer , Battistoni, Giorgia , Bressan, Dario , Naamati, Adi , Falciatori, Ilaria , Berkyurek, Ahmet Can , Rasnic, Roni , Izuagbe, Rhys , Hosmillo, Myra , Ilan, Shaul , Grossman, Iris , McCormick, Lauren , Honeycutt, Christopher Cole , Johnston, Timothy , Gagne, Matthew , Douek, Daniel C , Goodfellow, Ian , Hannon, Gregory James and Erlich, Yaniv
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Expanding the arsenal of prophylactic approaches against SARS-CoV-2 is of utmost importance, specifically those strategies that are resistant to antigenic drift in Spike. Here, we conducted a screen of over 16,000 RNAi triggers against the SARS-CoV-2 genome, using a massively parallel assay to identify hyper-potent siRNAs. We selected Ten candidate...
Alternative Titles
Full title
From a genome-wide screen of RNAi molecules against SARS-CoV-2 to a validated broad-spectrum and potent prophylaxis
Authors, Artists and Contributors
Author / Creator
Weissbrod, Omer
Battistoni, Giorgia
Bressan, Dario
Naamati, Adi
Falciatori, Ilaria
Berkyurek, Ahmet Can
Rasnic, Roni
Izuagbe, Rhys
Hosmillo, Myra
Ilan, Shaul
Grossman, Iris
McCormick, Lauren
Honeycutt, Christopher Cole
Johnston, Timothy
Gagne, Matthew
Douek, Daniel C
Goodfellow, Ian
Hannon, Gregory James
Erlich, Yaniv
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ff02faec80454a3f8bad5508748dbbd4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ff02faec80454a3f8bad5508748dbbd4
Other Identifiers
ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-023-04589-5
