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Neural differentiation of glioblastoma cell lines via a herpes simplex virus thymidine kinase/gancic...

Neural differentiation of glioblastoma cell lines via a herpes simplex virus thymidine kinase/gancic...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ff151a6af6bb4843b4b40a4b6510841b

Neural differentiation of glioblastoma cell lines via a herpes simplex virus thymidine kinase/ganciclovir system driven by a glial fibrillary acidic protein promoter

About this item

Full title

Neural differentiation of glioblastoma cell lines via a herpes simplex virus thymidine kinase/ganciclovir system driven by a glial fibrillary acidic protein promoter

Publisher

Public Library of Science (PLoS)

Journal title

PloS one, 2021-01, Vol.16 (8)

Language

English

Formats

Publication information

Publisher

Public Library of Science (PLoS)

More information

Scope and Contents

Contents

Glioblastoma is a malignant brain tumor with poor prognosis that rapidly acquires resistance to available clinical treatments. The herpes simplex virus thymidine kinase/ganciclovir (HSVtk/GCV) system produces the selective elimination of HSVtk-positive cells and is a candidate for preclinical testing against glioblastoma via its ability to regulate...

Alternative Titles

Full title

Neural differentiation of glioblastoma cell lines via a herpes simplex virus thymidine kinase/ganciclovir system driven by a glial fibrillary acidic protein promoter

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ff151a6af6bb4843b4b40a4b6510841b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ff151a6af6bb4843b4b40a4b6510841b

Other Identifiers

E-ISSN

1932-6203

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