PRIMA: a rapid and cost-effective genotyping method to detect single-nucleotide differences using pr...
PRIMA: a rapid and cost-effective genotyping method to detect single-nucleotide differences using probe-induced heteroduplexes
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Targeted mutagenesis by programmable site-specific nucleases like CRISPR typically produce 1-base pair (bp) insertion or deletion (indel) mutations. Although several methods have been developed to detect such 1-bp indels, each method has pros and cons in terms of cost and/or resolution. Heteroduplex mobility assay (HMA) is a traditional technique d...
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PRIMA: a rapid and cost-effective genotyping method to detect single-nucleotide differences using probe-induced heteroduplexes
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TN_cdi_doaj_primary_oai_doaj_org_article_ff32f2eb5afe48c7800979925e01dfb2
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ff32f2eb5afe48c7800979925e01dfb2
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-99641-x
