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Loss of the Coffin-Lowry syndrome associated gene RSK2 alters ERK activity, synaptic function and ax...

Loss of the Coffin-Lowry syndrome associated gene RSK2 alters ERK activity, synaptic function and ax...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ff388241fa294a1b914d53c8a2aeb4aa

Loss of the Coffin-Lowry syndrome associated gene RSK2 alters ERK activity, synaptic function and axonal transport in Drosophila motoneurons

About this item

Full title

Loss of the Coffin-Lowry syndrome associated gene RSK2 alters ERK activity, synaptic function and axonal transport in Drosophila motoneurons

Publisher

England: The Company of Biologists Ltd

Journal title

Disease models & mechanisms, 2015-11, Vol.8 (11), p.1389-1400

Language

English

Formats

Publication information

Publisher

England: The Company of Biologists Ltd

More information

Scope and Contents

Contents

Plastic changes in synaptic properties are considered as fundamental for adaptive behaviors. Extracellular-signal-regulated kinase (ERK)-mediated signaling has been implicated in regulation of synaptic plasticity. Ribosomal S6 kinase 2 (RSK2) acts as a regulator and downstream effector of ERK. In the brain, RSK2 is predominantly expressed in region...

Alternative Titles

Full title

Loss of the Coffin-Lowry syndrome associated gene RSK2 alters ERK activity, synaptic function and axonal transport in Drosophila motoneurons

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ff388241fa294a1b914d53c8a2aeb4aa

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ff388241fa294a1b914d53c8a2aeb4aa

Other Identifiers

ISSN

1754-8403,1754-8411

E-ISSN

1754-8411,1754-8403

DOI

10.1242/dmm.021246

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