Synthesis and Antiproliferative Activity of Novel Heterocyclic Glycyrrhetinic Acid Derivatives
Synthesis and Antiproliferative Activity of Novel Heterocyclic Glycyrrhetinic Acid Derivatives
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Switzerland: MDPI AG
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Language
English
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Switzerland: MDPI AG
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A new series of glycyrrhetinic acid derivatives has been synthesized via the introduction of different heterocyclic rings conjugated with an α,β-unsaturated ketone in its ring A. These new compounds were screened for their antiproliferative activity in a panel of nine human cancer cell lines. Compound 10 was the most active derivative, with an IC50...
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Synthesis and Antiproliferative Activity of Novel Heterocyclic Glycyrrhetinic Acid Derivatives
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TN_cdi_doaj_primary_oai_doaj_org_article_ff61abe3836b4e9d9ba442610a1e7f80
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ff61abe3836b4e9d9ba442610a1e7f80
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules24040766
