Enhanced effect of the immunosuppressive soluble HLA-G2 homodimer by site-specific PEGylation
Enhanced effect of the immunosuppressive soluble HLA-G2 homodimer by site-specific PEGylation
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Human leukocyte antigen (HLA)-G is a nonclassical HLA class I molecule that has an immunosuppressive effect mediated by binding to immune inhibitory leukocyte immunoglobulin-like receptors (LILR) B1 and LILRB2. A conventional HLA-G isoform, HLA-G1, forms a heterotrimeric complex composed of a heavy chain (α1-α3 domains), β2-microglobulin (β2m) and...
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Full title
Enhanced effect of the immunosuppressive soluble HLA-G2 homodimer by site-specific PEGylation
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TN_cdi_doaj_primary_oai_doaj_org_article_ff61e90416b84d3b82a0f67077d494cf
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ff61e90416b84d3b82a0f67077d494cf
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-85072-x
