1H-NMR metabolomics reveals the Glabrescione B exacerbation of glycolytic metabolism beside the cell...
1H-NMR metabolomics reveals the Glabrescione B exacerbation of glycolytic metabolism beside the cell growth inhibitory effect in glioma
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Author / Creator
D’Alessandro, Giuseppina , Quaglio, Deborah , Monaco, Lucia , Lauro, Clotilde , Ghirga, Francesca , Ingallina, Cinzia , De Martino, Michela , Fucile, Sergio , Porzia, Alessandra , Di Castro, Maria Amalia , Bellato, Federica , Mastrotto, Francesca , Mori, Mattia , Infante, Paola , Turano, Paola , Salmaso, Stefano , Caliceti, Paolo , Di Marcotullio, Lucia , Botta, Bruno , Ghini, Veronica and Limatola, Cristina
Publisher
London: BioMed Central Ltd
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Language
English
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Publisher
London: BioMed Central Ltd
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Contents
Glioma is the most common and primary brain tumors in adults. Despite the available multimodal therapies, glioma patients appear to have a poor prognosis. The Hedgehog (Hh) signaling is involved in tumorigenesis and emerged as a promising target for brain tumors. Glabrescione B (GlaB) has been recently identified as the first direct inhibitor of Gl...
Alternative Titles
Full title
1H-NMR metabolomics reveals the Glabrescione B exacerbation of glycolytic metabolism beside the cell growth inhibitory effect in glioma
Authors, Artists and Contributors
Author / Creator
Quaglio, Deborah
Monaco, Lucia
Lauro, Clotilde
Ghirga, Francesca
Ingallina, Cinzia
De Martino, Michela
Fucile, Sergio
Porzia, Alessandra
Di Castro, Maria Amalia
Bellato, Federica
Mastrotto, Francesca
Mori, Mattia
Infante, Paola
Turano, Paola
Salmaso, Stefano
Caliceti, Paolo
Di Marcotullio, Lucia
Botta, Bruno
Ghini, Veronica
Limatola, Cristina
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ff7751943fc1431e869c9fb22d5bcc4c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ff7751943fc1431e869c9fb22d5bcc4c
Other Identifiers
ISSN
1478-811X
E-ISSN
1478-811X
DOI
10.1186/s12964-019-0421-8