Helicobacter pylori FabX contains a [4Fe-4S] cluster essential for unsaturated fatty acid synthesis
Helicobacter pylori FabX contains a [4Fe-4S] cluster essential for unsaturated fatty acid synthesis
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Zhou, Jiashen , Zhang, Lin , Zeng, Liping , Yu, Lu , Duan, Yuanyuan , Shen, Siqi , Hu, Jingyan , Zhang, Pan , Song, Wenyan , Ruan, Xiaoxue , Jiang, Jing , Zhang, Yinan , Zhou, Lu , Jia, Jia , Hang, Xudong , Tian, Changlin , Lin, Houwen , Chen, Hong-Zhuan , Cronan, John E. , Bi, Hongkai and Zhang, Liang
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Unsaturated fatty acids (UFAs) are essential for functional membrane phospholipids in most bacteria. The bifunctional dehydrogenase/isomerase FabX is an essential UFA biosynthesis enzyme in the widespread human pathogen
Helicobacter pylori
, a bacterium etiologically related to 95% of gastric cancers. Here, we present the crystal structures o...
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Full title
Helicobacter pylori FabX contains a [4Fe-4S] cluster essential for unsaturated fatty acid synthesis
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TN_cdi_doaj_primary_oai_doaj_org_article_ff98c86182784a2baf66ddf02f8bcbf9
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ff98c86182784a2baf66ddf02f8bcbf9
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-27148-0
