Impact of mouse contamination in genomic profiling of patient-derived models and best practice for r...
Impact of mouse contamination in genomic profiling of patient-derived models and best practice for robust analysis
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Contents
Patient-derived xenograft and cell line models are popular models for clinical cancer research. However, the inevitable inclusion of a mouse genome in a patient-derived model is a remaining concern in the analysis. Although multiple tools and filtering strategies have been developed to account for this, research has yet to demonstrate the exact imp...
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Full title
Impact of mouse contamination in genomic profiling of patient-derived models and best practice for robust analysis
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TN_cdi_doaj_primary_oai_doaj_org_article_ff9da52be4a84c0285e009c0370de591
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ff9da52be4a84c0285e009c0370de591
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ISSN
1474-760X,1474-7596
E-ISSN
1474-760X
DOI
10.1186/s13059-019-1849-2
