Genotoxic stress-triggered β-catenin/JDP2/PRMT5 complex facilitates reestablishing glutathione homeo...
Genotoxic stress-triggered β-catenin/JDP2/PRMT5 complex facilitates reestablishing glutathione homeostasis
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Author / Creator
Cao, Lixue , Wu, Geyan , Zhu, Jinrong , Tan, Zhanyao , Shi, Dongni , Wu, Xingui , Tang, Miaoling , Li, Ziwen , Hu, Yameng , Zhang, Shuxia , Yu, Ruyuan , Mo, Shuang , Wu, Jueheng , Song, Erwei , Li, Mengfeng , Song, Libing and Li, Jun
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The mechanisms underlying how cells subjected to genotoxic stress reestablish reduction-oxidation (redox) homeostasis to scavenge genotoxic stress-induced reactive oxygen species (ROS), which maintains the physiological function of cellular processes and cell survival, remain unclear. Herein, we report that, via a TCF-independent mechanism, genotox...
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Full title
Genotoxic stress-triggered β-catenin/JDP2/PRMT5 complex facilitates reestablishing glutathione homeostasis
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ffab176b40414791a1654754dbf0a80b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ffab176b40414791a1654754dbf0a80b
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-11696-7