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Fargesin ameliorates osteoarthritis via macrophage reprogramming by downregulating MAPK and NF-κB pa...

Fargesin ameliorates osteoarthritis via macrophage reprogramming by downregulating MAPK and NF-κB pa...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ffc263b0c14c4fd49e8d292885e11603

Fargesin ameliorates osteoarthritis via macrophage reprogramming by downregulating MAPK and NF-κB pathways

About this item

Full title

Fargesin ameliorates osteoarthritis via macrophage reprogramming by downregulating MAPK and NF-κB pathways

Publisher

England: BioMed Central

Journal title

Arthritis research & therapy, 2021-05, Vol.23 (1), p.142-142, Article 142

Language

English

Formats

Publication information

Publisher

England: BioMed Central

More information

Scope and Contents

Contents

To investigate the role and regulatory mechanisms of fargesin, one of the main components of Magnolia fargesii, in macrophage reprogramming and crosstalk across cartilage and synovium during osteoarthritis (OA) development.
Ten-week-old male C57BL/6 mice were randomized and assigned to vehicle, collagenase-induced OA (CIOA), or CIOA with intra-a...

Alternative Titles

Full title

Fargesin ameliorates osteoarthritis via macrophage reprogramming by downregulating MAPK and NF-κB pathways

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ffc263b0c14c4fd49e8d292885e11603

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ffc263b0c14c4fd49e8d292885e11603

Other Identifiers

ISSN

1478-6362,1478-6354

E-ISSN

1478-6362

DOI

10.1186/s13075-021-02512-z

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