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Cancer immune control needs senescence induction by interferon-dependent cell cycle regulator pathwa...

Cancer immune control needs senescence induction by interferon-dependent cell cycle regulator pathwa...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ffeefb0c18174583b0c353a1c64a24f9

Cancer immune control needs senescence induction by interferon-dependent cell cycle regulator pathways in tumours

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Immune checkpoint blockade (ICB)-based or natural cancer immune responses largely eliminate tumours. Yet, they require additional mechanisms to arrest those cancer cells that are not rejected. Cytokine-induced senescence (CIS) can stably arrest cancer cells, suggesting that interferon-dependent induction of senescence-inducing cell cycle regulators...

Alternative Titles

Full title

Cancer immune control needs senescence induction by interferon-dependent cell cycle regulator pathways in tumours

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ffeefb0c18174583b0c353a1c64a24f9

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ffeefb0c18174583b0c353a1c64a24f9

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-14987-6

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