Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens
Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens
About this item
Full title
Author / Creator
Hwang, Michael S. , Miller, Michelle S. , Thirawatananond, Puchong , Douglass, Jacqueline , Wright, Katharine M. , Hsiue, Emily Han-Chung , Mog, Brian J. , Aytenfisu, Tihitina Y. , Murphy, Michael B. , Aitana Azurmendi, P. , Skora, Andrew D. , Pearlman, Alexander H. , Paul, Suman , DiNapoli, Sarah R. , Konig, Maximilian F. , Bettegowda, Chetan , Pardoll, Drew M. , Papadopoulos, Nickolas , Kinzler, Kenneth W. , Vogelstein, Bert , Zhou, Shibin , Gabelli, Sandra B. and Brookhaven National Laboratory (BNL), Upton, NY (United States)
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Chimeric antigen receptor (CAR) T cells have emerged as a promising class of therapeutic agents, generating remarkable responses in the clinic for a subset of human cancers. One major challenge precluding the wider implementation of CAR therapy is the paucity of tumor-specific antigens. Here, we describe the development of a CAR targeting the tumor...
Alternative Titles
Full title
Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens
Authors, Artists and Contributors
Author / Creator
Miller, Michelle S.
Thirawatananond, Puchong
Douglass, Jacqueline
Wright, Katharine M.
Hsiue, Emily Han-Chung
Mog, Brian J.
Aytenfisu, Tihitina Y.
Murphy, Michael B.
Aitana Azurmendi, P.
Skora, Andrew D.
Pearlman, Alexander H.
Paul, Suman
DiNapoli, Sarah R.
Konig, Maximilian F.
Bettegowda, Chetan
Pardoll, Drew M.
Papadopoulos, Nickolas
Kinzler, Kenneth W.
Vogelstein, Bert
Zhou, Shibin
Gabelli, Sandra B.
Brookhaven National Laboratory (BNL), Upton, NY (United States)
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_fff72ea490f640af8b0aeee032442ea5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_fff72ea490f640af8b0aeee032442ea5
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-25605-4
