Development and optimization of a self-microemulsifying drug delivery system for atorvastatin calciu...
Development and optimization of a self-microemulsifying drug delivery system for atorvastatin calcium by using D-optimal mixture design
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Publisher
New Zealand: Dove Medical Press Limited
Journal title
Language
English
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Publisher
New Zealand: Dove Medical Press Limited
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Scope and Contents
Contents
In this study, we developed and optimized a self-microemulsifying drug delivery system (SMEDDS) formulation for improving the dissolution and oral absorption of atorvastatin calcium (ATV), a poorly water-soluble drug. Solubility and emulsification tests were performed to select a suitable combination of oil, surfactant, and cosurfactant. A D-optima...
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Full title
Development and optimization of a self-microemulsifying drug delivery system for atorvastatin calcium by using D-optimal mixture design
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TN_cdi_dovepress_primary_oai_dovepress_com_22035
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_dovepress_primary_oai_dovepress_com_22035
Other Identifiers
ISSN
1178-2013,1176-9114
E-ISSN
1178-2013
DOI
10.2147/IJN.S83520
