Beta-Amyloid Downregulates MDR1-P-Glycoprotein (Abcb1) Expression at the Blood-Brain Barrier in Mice
Beta-Amyloid Downregulates MDR1-P-Glycoprotein (Abcb1) Expression at the Blood-Brain Barrier in Mice
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Cairo, Egypt: Hindawi Puplishing Corporation
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English
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Publisher
Cairo, Egypt: Hindawi Puplishing Corporation
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Neurovascular dysfunction is an important component of Alzheimer's disease, leading to reduced clearance across the blood-brain barrier and accumulation of neurotoxic β-amyloid (Aβ) peptides in the brain. It has been shown that the ABC transport protein P-glycoprotein (P-gp, ABCB1) is involved in the export of Aβ from the brain into the blood. To d...
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Beta-Amyloid Downregulates MDR1-P-Glycoprotein (Abcb1) Expression at the Blood-Brain Barrier in Mice
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TN_cdi_emarefa_primary_490779
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_emarefa_primary_490779
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ISSN
2090-8024
E-ISSN
2090-0252