Log in to save to my catalogue

Beta-Amyloid Downregulates MDR1-P-Glycoprotein (Abcb1) Expression at the Blood-Brain Barrier in Mice

Beta-Amyloid Downregulates MDR1-P-Glycoprotein (Abcb1) Expression at the Blood-Brain Barrier in Mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_emarefa_primary_490779

Beta-Amyloid Downregulates MDR1-P-Glycoprotein (Abcb1) Expression at the Blood-Brain Barrier in Mice

About this item

Full title

Beta-Amyloid Downregulates MDR1-P-Glycoprotein (Abcb1) Expression at the Blood-Brain Barrier in Mice

Publisher

Cairo, Egypt: Hindawi Puplishing Corporation

Journal title

International journal of alzheimer's disease, 2011, Vol.2011 (2011), p.1-6

Language

English

Formats

Publication information

Publisher

Cairo, Egypt: Hindawi Puplishing Corporation

More information

Scope and Contents

Contents

Neurovascular dysfunction is an important component of Alzheimer's disease, leading to reduced clearance across the blood-brain barrier and accumulation of neurotoxic β-amyloid (Aβ) peptides in the brain. It has been shown that the ABC transport protein P-glycoprotein (P-gp, ABCB1) is involved in the export of Aβ from the brain into the blood. To d...

Alternative Titles

Full title

Beta-Amyloid Downregulates MDR1-P-Glycoprotein (Abcb1) Expression at the Blood-Brain Barrier in Mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_emarefa_primary_490779

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_emarefa_primary_490779

Other Identifiers

ISSN

2090-8024

E-ISSN

2090-0252

How to access this item