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Facilitated Cross-Bridge Interactions with Thin Filaments by Familial Hypertrophic Cardiomyopathy Mu...

Facilitated Cross-Bridge Interactions with Thin Filaments by Familial Hypertrophic Cardiomyopathy Mu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_emarefa_primary_990094

Facilitated Cross-Bridge Interactions with Thin Filaments by Familial Hypertrophic Cardiomyopathy Mutations in α-Tropomyosin

About this item

Full title

Facilitated Cross-Bridge Interactions with Thin Filaments by Familial Hypertrophic Cardiomyopathy Mutations in α-Tropomyosin

Publisher

Cairo, Egypt: Hindawi Publishing Corporation

Journal title

BioMed research international, 2011, Vol.2011 (2011), p.1-12

Language

English

Formats

Publication information

Publisher

Cairo, Egypt: Hindawi Publishing Corporation

More information

Scope and Contents

Contents

Familial hypertrophic cardiomyopathy (FHC) is a disease of cardiac sarcomeres. To identify molecular mechanisms underlying FHC pathology, functional and structural differences in three FHC-related mutations in recombinant α-Tm (V95A, D175N, and E180G) were characterized using both conventional and modified in vitro motility assays and circular dich...

Alternative Titles

Full title

Facilitated Cross-Bridge Interactions with Thin Filaments by Familial Hypertrophic Cardiomyopathy Mutations in α-Tropomyosin

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_emarefa_primary_990094

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_emarefa_primary_990094

Other Identifiers

ISSN

2314-6133

E-ISSN

2314-6141

DOI

10.1155/2011/435271

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