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Micromechanical Thermal Assays of Ca2+-Regulated Thin-Filament Function and Modulation by Hypertroph...

Micromechanical Thermal Assays of Ca2+-Regulated Thin-Filament Function and Modulation by Hypertroph...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_emarefa_primary_991828

Micromechanical Thermal Assays of Ca2+-Regulated Thin-Filament Function and Modulation by Hypertrophic Cardiomyopathy Mutants of Human Cardiac Troponin

About this item

Full title

Micromechanical Thermal Assays of Ca2+-Regulated Thin-Filament Function and Modulation by Hypertrophic Cardiomyopathy Mutants of Human Cardiac Troponin

Publisher

Cairo, Egypt: Hindawi Publishing Corporation

Journal title

BioMed research international, 2012, Vol.2012 (2012), p.1-13

Language

English

Formats

Publication information

Publisher

Cairo, Egypt: Hindawi Publishing Corporation

More information

Scope and Contents

Contents

Microfabricated thermoelectric controllers can be employed to investigate mechanisms underlying myosin-driven sliding of Ca2+-regulated actin and disease-associated mutations in myofilament proteins. Specifically, we examined actin filament sliding—with or without human cardiac troponin (Tn) and α-tropomyosin (Tm)—propelled by rabbit skeletal heavy...

Alternative Titles

Full title

Micromechanical Thermal Assays of Ca2+-Regulated Thin-Filament Function and Modulation by Hypertrophic Cardiomyopathy Mutants of Human Cardiac Troponin

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_emarefa_primary_991828

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_emarefa_primary_991828

Other Identifiers

ISSN

2314-6133

E-ISSN

2314-6141

DOI

10.1155/2012/657523

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