Rel/NF-kappa B double mutants reveal that cellular immunity is central to Drosophila host defense
Rel/NF-kappa B double mutants reveal that cellular immunity is central to Drosophila host defense
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National Academy of Sciences
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English
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National Academy of Sciences
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Studies on Drosophila immunity have focused on the humoral response, whereas less is known about the Drosophila cellular immunity. Here we show that mutants that lack the Drosophila Rel/NF-kappa B proteins Dorsal and Dif have very few blood cells, are constitutively infected by opportunistic microbes, and die from infection as larvae. When the doub...
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Rel/NF-kappa B double mutants reveal that cellular immunity is central to Drosophila host defense
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TN_cdi_fao_agris_US201300763126
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201300763126
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0605721103
