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Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin

Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201300870692

Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin

About this item

Full title

Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2008-03, Vol.105 (10), p.3945-3950

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Acute myeloid leukemia (AML) carrying NPM1 mutations and cytoplasmic nucleophosmin (NPMc+ AML) accounts for about one-third of adult AML and shows distinct features, including a unique gene expression profile. MicroRNAs (miRNAs) are small noncoding RNAs of 19-25 nucleotides in length that have been linked to the development of cancer. Here, we inve...

Alternative Titles

Full title

Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_fao_agris_US201300870692

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_fao_agris_US201300870692

Other Identifiers

ISSN

0027-8424,1091-6490

E-ISSN

1091-6490

DOI

10.1073/pnas.0800135105

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